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Upcoming webinar: “DZNE and HPE: Harnessing Memory-Driven Computing to fight Alzheimer’s disease"



Last July we announced our first collaboration with the German Center for Neurodegenerative Diseases (DZNE). The organization is using Memory-Driven Computing architecture, the largest in-memory system on the planet, to research Alzheimer’s, a disease that affects one in 10 people age 65 or older in the world.[1]

To accelerate their search for a cure, they needed a new kind of computer to manipulate their massive data sets. The Machine provided a 160 terabyte prototype based on the world’s first Memory-Driven Computing architecture.


The initial findings are powerful and promising.  They only started to scratch the surface with one component of their overall data analytics pipeline and are already getting over 40x speed improvements. In practical terms, that means they are getting results that used to take more than 22 minutes in less than three. These gains could increase up to 100X when they expand what they have learned to the other components of their pipeline. In an industry where saved time translates to helping saved lives, these efficiencies could change the game.

We’re excited to have Hartmut Schultze, Engagement Manager at Hewlett Packard Enterprise, Dr. Matthias Becker, postdoctoral researcher at the University of Bonn in Germany, and Prof. Joachim Schulze, Prof. Dr. Joachim L. Schultze, Funding Director, PRECISE – Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn,  share their story in the next webinar through The Machine User Group.

In this webinar, they will present how small changes in existing tools can lead to significant performance benefits. The focus will be on two approaches: First, by using the Librarian File System and memory-mapping, data access can be accelerated and be freed from assumptions on linear reading. Second, the abundance of memory can be used to consider different data structures for internal state to be demonstrated on a hash map example.

You can learn more about our work with DZNE on our Hewlett Packard Labs blog and “Fighting Oblivion with a New Kind of Computer” HPE newsroom blog.

Sign up for the “DZNE and HPE: Harnessing Memory-Driven Computing to fight Alzheimer’s disease” webinar on Tuesday, October 10, 7 am – 8:15 am pacific time. 

 We look forward to seeing on there!






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David Fahrland

Hello. What Operating System does The Machine  run  on? Is Realtime? An HP variant of  UNIX or something completely new & different ? Thank you


Hi @David Fahrland - thanks for your comment and for following our blog! 

The Machine's Linux operating system would be formally classified as a Debian derivative and is fully open source. There is an emulation environment currently available: Fabric Attached Memory Emulation, that is openly available on Github under the Fabric Attached Memory project:

You can also learn more about the rest of the open-source Memory-Driven Computing Developer Toolkit here:

Thanks! Martina Trucco, Hewlett Packard Labs

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