Proliant ML350 G5 networking dies on large data transfer

[Sue Rathbone]

The NIC thinks it is still happy, however it cannot send or receive packets. A reboot will refresh the NIC, however the data transfer still breaks. The sending server says it can no longer find the network path. If you give it a day or so, you can start the transfer again. After a fashion, it will die yet again. No patterns, rhyme, or reason. NIC was tested. Drivers updated. Virus and spyware free. Cables changed. No errors on the port. Happens on the C drive as well as the external eSATA and USB hard drives. Transfer of same data to another workstation in the same domain works fine.
Thoughts?

[Guido Elia]

Is the server multihomed and you have more than one default gateway ?

[Sue Rathbone]

It has an integrated dual homed NIC. Only one default gateway. Static IP.

[Guido Elia]

Try a tracert to the destination IP before and after the issue

[Sue Rathbone]

It's only one hop anyway as it's just down the hall.