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DL370 G6 SAS Disk Drives, SFF vs LFF reliability

 
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DL370 G6 SAS Disk Drives, SFF vs LFF reliability

I'm looking at the new DL370 G6 server as a candidate for a Oracle Linux Database Server. It will run a very important application that I can't really afford much downtime due to drive failures, and it seems these days that all brands and models of hard drives are nowhere as reliable as they used to be a few years ago.

Is there a significant difference in the long term reliability of the 2.5" Small Form Factor SAS hard drives versus the 3.5" Large Form Factor drives?

I will, of course, be running RAID1 on the operating system volume, and RAID10 on the application and database volumes.