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Transforming Genomic Analytics with HPC-Accelerated Insights



Intel and the Broad Institute have partnered to fuel genomics research, and HPE is joining forces with these leaders to help organizations leverage HPC-driven insights, drive genomic analytics, and enhance patient care.

Advancements in the field of genomics are revolutionizing our understanding of human biology, rapidly accelerating the discovery and treatment of genetic diseases, and dramatically improving human health. Genomics, the study of genetic material, is allowing medical professionals to enhance clinical care based on their patients’ specific genetic makeup. And thanks to ongoing IT innovations, genomic research is moving the industry toward a promising future of personalized healthcare and precision medicine.

To facilitate this transition, Intel and the Broad Institute of MIT and Harvard—in collaboration with Hewlett Packard Enterprise (HPE)—have partnered to ramp up genomic analytics workflows, at unprecedented scale, and with easier deployment. Sharing a common vision to uncover better methods of acquiring, processing, storing, and analyzing genomic data, these organizations offer a series of powerful and flexible data center solutions incorporating best-of-breed hardware and optimized software that will enhance researchers’ ability to analyze genomic datasets collected from diverse sources.

The Genome Analysis Toolkit from the Broad Institute is the industry’s foremost software tool in the field of genomic analytics. The fourth version of this software package (designated GATK4) is available under an open soNGSBlog.jpgurce software license to help researchers eliminate infrastructure-related complications and derive insights from large genomic datasets in an easier, faster, and more efficient way.

Intel and the Broad have developed a breakthrough reference architecture called the Broad-Intel Genomics Stack (BIGstack), which delivers 5X improvement to the Broad’s genomics analytics pipeline. Through this partnership, the BIGstack will drive global alignment in the rapidly growing genomics community.

As an original equipment manufacturer (OEM) partner, HPE solutions are the foundation of this breakthrough architecture. HPE has developed a purpose-built, unified compute and storage solution that is optimally designed for NGS workflows, delivering the throughput and efficiency needed to keep pace with the growing demand for genome analysis. Utilizing high performance computing (HPC) solutions such as HPE Apollo systems and HPE ProLiant servers, researchers can leverage the speed and performance necessary to power advanced data analysis techniques—such as artificial intelligence (AI) and deep learning capabilities.

Powered by Intel Xeon Phi processors, users can harness breakthrough levels of performance to eliminate bottlenecks, support data-heavy workloads, and scale seamlessly to accommodate tomorrow’s challenges. These technologies enable researchers to rapidly train deep neural networks on robust, scalable infrastructure to accelerate AI and genomic insights. Additionally, the Intel Scalable System Framework is a holistic solution that optimizes compute- and data-intensive processes as well as deep learning techniques to reduce time to insight.

The field of genomics is experiencing a major paradigm shift, and developments over the next decade will undoubtedly accelerate the use of technologies like HPC and AI across the industry. As leaders in their respective fields, Intel and the Broad Institute are working together to develop solutions that will help researchers overcome the challenges of diverse genomic datasets, and speed time to results. HPE is proud to contribute to this milestone in advancing genomics research.

The powerful HPE and Intel HPC Alliance is driving major improvements to a variety of enterprise operations—and genomic analytics is just the beginning. To learn more about how these cutting-edge capabilities are revolutionizing the life sciences industry, I invite you to follow me on Twitter at @pango. You can also check out @HPE_HPC and @IntelHPC for up-to-the-minute news and updates on the latest innovations in HPC, AI/deep learning, supercomputing, and more.

Pankaj Goyal
Vice President, HPE AI Business
Hewlett Packard Enterprise

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About the Author


Pankaj is building HPE’s Artificial Intelligence business. He is excited by the potential of AI to improve our lives, and believes HPE has a huge role to play. In his past life, he has been a computer science engineer, an entrepreneur, and a strategy consultant. Reach out to him to discuss everything AI @HPE.