Just a note: HP-UX, like all flavors of Unix, is critically dependent on files in order to run. Every time a file is opened, an entry must be made in a table in the operating system. If all the file entries are occupied, not even root can login because login needs to open several files, so yes, HP-UX will appear to be down. This is not a bug, it is a feature.
Now in the above error message, it as been repeated 215,000 times in one minute and that is definitely not normal. Some process is trying to open a file continuously rather than terminating normally. A simple shell script created by a novice user (does not have to be root) could devastate your system in this manner. Or it may just be java threads going crazy because of a programming error. Idf changing nfile to 30,000 (and regenerating the kernel and reboting) does not help, you definitely have a runaway program or script that needs to be terminated.
Bill Hassell, sysadmin