Upgraded or a new install of HPSIM?
For the initial use of HPSIM; SSH & WBEM can be ignored.
Additional Accounts can be created using the Options/Security/Authorizations and Users Page.
This allows different levels of access to the CMS.
HPSIM can be used at this point, Discovery etc. will work.
SSH is set up on the CMS Server to allow Custom Commands to run. You'll need to deploy SSH to other Servers if you want Custom Commands to be able to be run on those Servers from the CMS. It's not necessary for general HPSIM Operation.
WBEM Access, depends on what Servers you've got, but it seems as though this is needed for the new CPM to work.
The Management Agent on the CMS, there's been a big change here, Authorization is changing from the old 3 accounts controlled by the app. to authentication by the System.
This also affects how the VCA/VCRM works.
I've added our domain\domainadmins as a Group and created a local account for the VCA and added that.