Hi,
ISEE Clients send data to the SPOP (or directly to HP) using port 80, this is http protocol and cannot be changed.
The SPOP (if you have one) sends data to HP over port 443, this is https standard protocol and once again, this cannot be changed.
So, if you have Clients in a DMZ, you'll need to open port 80 (outbound with established back) to the SPOP.
There are other "optional" applications such as UDN, telnet, ftp, SMTP which may require additional ports. Please refer to the SPOP Install & Upgrade Guide for more info.
Hope this helps,
Regards,