Discover how HPE ProLiant Compute Gen12 servers with AMD EPYC processors can revolutionize your virtualization strategy, reduce costs, and boost efficiency.
The HPE ProLiant Compute Gen12 portfolio, recently expanded with two new models featuring AMD EPYC processors, delivers high-density performance, better efficiency, and smarter operations for today’s virtualized environments.
Why your virtualization strategy may no longer fit
Virtualization remains essential to enterprise IT. But many environments have quietly drifted from their original design. What began as a lean, cost-saving solution has expanded to support remote users, edge sites, hybrid clouds, and increasingly complex workloads. Even well-managed systems can become mismatched with today’s needs.
For many organizations, that mismatch shows up in subtle but compounding ways: rising licensing costs, provisioning delays, and infrastructure that can’t quite keep up with AI, analytics, or VDI demands.
Addressing these challenges demands modernization — not just of hardware, but of the strategy itself. Modernizing is about realigning infrastructure and licensing with the way your organization actually works today and the way it needs to grow tomorrow. That means consolidating virtual environments, rethinking resource allocation, and choosing platforms built to perform at scale.
Purpose-built for virtualization: Meet the HPE ProLiant Compute Gen12 DL325 and DL345
HPE ProLiant Compute Gen12 servers featuring the latest AMD EPYC processors are designed with virtualization in mind, offering high-density performance, impressive memory capacity, and power-efficient architecture tailored for demanding workloads.
Key highlights include:
- DL325 and DL345 models purpose-built for virtualization, containers, and VDI
- Up to 2X more memory versus previous generations, supporting up to 6TB
- Up to 192 cores and 500W for VM-per-host efficiency
- Enhanced cooling with option direct-liquid cooling and closed loop liquid cooling (DL325)
- HPE iLO 7, HPE’s industry-leading security IP that builds protection at the silicon level to protect against threats
The TCO case for refreshing your infrastructure now
Refreshing outdated infrastructure with newer, more efficient systems can dramatically lower your total cost of ownership across hardware, energy, and virtualization software.
Here’s what HPE ProLiant Compute Gen12 servers delivers compared to older platforms:
- Up to 7:1 server consolidation
- Up to 65% power savings vs Gen10 systems
- Up to 27% savings on VM software licensing
- Even greater savings when moving from Gen8 or Gen9 — up to 84% power savings and 14:1 or 26:1 consolidation potential
These gains aren’t hypothetical. They’re based on internal HPE testing, and they translate directly into budget relief, sustainability progress, and freed-up capacity for innovation.
For IT leaders grappling with aging systems and tight budgets, the equation is simple: continue paying the hidden costs of “working” infrastructure or modernize and regain control.
Optimize licensing and cut virtualization software costs
As virtualization software costs rise — driven by licensing model shifts across the industry — many IT teams are looking for a flexible alternative to traditional platforms.
HPE Morpheus VM Essentials Software offers a unified management interface for both KVM-based HPE VME and existing VMware environments. It includes enterprise-grade features like live migration, high availability, automated provisioning, and integrated data protection. Because it's priced per CPU socket (not per core), it can help organizations reduce virtualization licensing expenses by up to 90% compared to legacy platforms.
When paired with HPE ProLiant Compute Gen12 servers, HPE Morpheus VM Essentials becomes part of a modern virtualization stack that is both purpose-built for performance and smartly priced. Whether you're scaling edge sites or consolidating data center workloads, this combination aligns with your current and future cloud-first needs.
Automated operations with AI-driven insights
Modern workloads demand modern operations. HPE Compute Ops Management is a secure, cloud-native platform that simplifies and automates key server lifecycle tasks — freeing up IT resources while improving efficiency across data center, edge, and hybrid environments.
HPE Compute Ops Management simplifies tasks like:
- Server provisioning and firmware updates — up to 5x faster than manual processes, with zero-touch provisioning and policy-based automation
• Forecasting energy use and emissions — using AI-powered insights to help teams plan for cost and sustainability goals
• Monitoring system health and compliance — across HPE and multi-vendor infrastructure, with built-in analytics to identify issues early
• Receiving real-time alerts and AI-driven recommendations — to optimize performance and resolve problems before they impact operations
Customers using HPE COM report up to 75% reduction in server management time.1 It’s a huge win for stretched teams managing complex infrastructure at scale.
Built-in security from chip to cloud
Security can’t be an afterthought — especially in today’s threat landscape. HPE ProLiant Compute Gen12 servers feature HPE iLO 7, delivering a secure, silicon-rooted foundation with advanced capabilities designed to protect against both current and emerging threats.
Key features include:
- Embedded secure enclave for advanced encryption key storage
- Quantum-resistant firmware signing (aligned to NIST and CNSA 2.0)
- Pursuing FIPS 140-3 Level 3 certification
- Tamper resistant monitoring and a trusted supply chain from rack to decommissioning
These protections ensure that your infrastructure isn’t just powerful — it’s prepared. With HPE ProLiant Compute Gen12, security is built-in from the factory, not bolted on after deployment.
Ready for what’s now and what’s next
With rising licensing costs, aging infrastructure, and growing complexity, the case for server modernization is compelling.
HPE ProLiant Compute Gen12 servers powered by AMD are purpose-built to help you simplify operations, lower costs, and set your organization up for future growth — whether you're consolidating VMs, moving to hybrid cloud, or preparing for AI-driven workloads.
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¹Forrester Consulting, New Technology: The Projected Total Economic Impact™ of HPE Compute Ops Management, a commissioned study conducted by Forrester Consulting on behalf of HPE, June 2024. https://tei.forrester.com/go/hpe/computeopsmanagement
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